OriginPro - Data Analysis Management software

OriginPro offers all of the features of Origin plus extended analysis tools in the following areas:

1. Peak Fitting
2. Surface Fitting
3. Statistics
4. Signal Processing
5. Image Handling

Peak Fitting
The Peak Analyzer tool in OriginPro provides the additional capability of finding and fitting multiple peaks in your spectra. Baseline anchor points can be customized and fit with a suitable fitting function, and the baseline fitting can be included as part of the final peak fitting process. A detailed Fit Control dialog is provided to control all aspects of peak fitting including mixed peak functions, peak centers and widths, sharing parameters, and imposing bounds and linear constraints on parameters. Graphical as well as tabular results are generated as part of the final fit report.

Surface Fitting
OriginPro can fit a 3D surface to XYZ data points. The surface and data points can be displayed together, including droplines from the points to the surface.

Statistics
OriginPro expands on the statistical analysis capabilities of Origin by providing additional tools in Descriptive Statistics, Discrete Frequency counting, normality tests, correlation analysis, one-way and two-way Repeated Measures ANOVA, many nonparametric tests such as Friedman ANOVA and Two-Sample Kolmogorov-Smirnov Test and Mann-Whitney Test, Survival Analysis tools including Weibull Fit and Cox Proprotional Hazard Model, ROC Curves, and Power and Sample Size tests.

Signal Processing
Advanced signal processing features in OriginPro include Short-Time FFT (STFT), Hilbert Transform, Coherence, 2D FFT and 2D FFT-based Filtering, 2D Correlation, and Wavelet analysis.

Image Handling
OriginPro offers more ways to handle your image data, including alpha blending, pixel logic, morphological filtering, and interpolated background subtraction.

Analytical Power
With so much analytical power, OriginPro is the software of choice for those who want a single data analysis and graphing solution.

Software Link: OriginPro - Data Analysis Management software

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BioRS™ Integration and Retrieval System

BioRS™ Integration and Retrieval System
The BioRS™ Integration and Retrieval System allows multiple public, commercial and proprietary databases to be combined and integrated into a unified environment. Flat-file and relational databases (inclucing Oracle® and MySQL™) with diverse formats are easily integrated using Web or command-line interfaces and standardized data formats based on Extensible Markup Language (XML).

Retrieve data conveniently
The BioRS Integration and Retrieval System quickly and efficiently retrieves biological data from public and proprietary databases. Researchers can easily search multiple, diverse databases simultaneously with a single query. The following are just a few examples:
Show protein information from UniProt together with information from EMBL
Select genes from BioRS query results and retrieve similar sequences from your proprietary database
Find all human kinases with transmembrane domains which are associated with liver cancer
Retrieve specific bacterial genes for antibiotic resistance and export them to plan cloning experiments
Download a list of all plant storage proteins for input into pattern searches to find protease cleavage sites

Connect data, connect teams
Scientists can locate related information from multiple sources using extensive cross-linking between databases and combined reports. A convenient database search environment is provided for diverse users - whether occasional user, every-day user or expert. Convenient tools are available for viewing and exporting retrieved information, and additional tools can be integrated as necessary.

Share data securely
The BioRS system ensures security within a distributed environment and allows safe data sharing among members of a large group in multiple locations. Because the BioRS system does not require Internet access, maximal confidentiality is ensured. Resource and user management is available using convenient Web and command-line interfaces. Individual users and user groups can be assigned privileges for controlling access to sensitive information.

The BioRS system as an information backbone
The BioRS system can be run as a stand-alone data integration and retrieval system or, alternatively, can be used as an information backbone supporting other software, such as the Pedant-Pro and BioXM systems. The screenshot below shows the BioRS system running as middleware for the BioXM Knowledge Management Environment.

Software Link:  BioRS™ Integration and Retrieval System

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ActivityBase Suite - Data Management Software

ActivityBase Suite is the world's leading solution for high volume routine screening, through to low throughput data management in large and small organizations. It is proven to efficiently and effectively manage small and large molecule research, ranging from drug discovery to biofuel innovation.

Scalable - Store and register any HTS, HCS and low throughput campaigns
Secure - Real time data analysis with built in quality control (QC) and business rules
Automate - Plate and non-plate based test design and mapping, accelerating analysis
Link - Directly to instruments for error free data import and analysis

Software Link:  ActivityBase Suite - Data Management Software

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MDCStore - Data Management Tool

MDCStore Data Management Solution for High Content Screening

Whether you operate in a small research lab or a large screening facility, make sure that all your imaging data is securely stored and fully accessible from the first image acquired to years of usage.

For Molecular Devices, to perform High Content Screening (HCS) in days instead of weeks doesn't only mean "to acquire and analyze millions of images." It also means managing the data deluge and being "able to connect the dots" to make the right decisions.

HCS instruments and High Content Analysis (HCA) generate daunting amounts of images, image segmentation, and extracted features; it is common to accumulate 5 terabytes of data for a 20,000 compound screen. The MDCStore™ Data Management Solution provides a powerful environment for HCS data storage, making it available for further analysis, and managing it over time. This organization of the HCS workflow allows you to make meaningful decisions from immense volumes of data and answer questions that cannot be answered without a proper management solution:
Does the same experimental condition have the same effect in multiple screens?
Is an outlier in a dose response an interesting phenotype or just a QC issue?
Are other experimental conditions producing images similar to this one?

The MDCStore Data Management Solution seamlessly integrates with the Molecular Devices complete set of tools for image acquisition (ImageXpress® confocal and widefield instruments), image analysis (MetaXpress® and MetaXpress® PoweCore™ Software), and cellular informatics (AcuityXpress™ Software), providing off-the-shelf capabilities to generate and interrogate data. A software development kit (SDK) is also available to enable communication with 3rd party hardware and software, integrate MDCStore Data Manager into an existing workflow, or facilitate additional applications.

Simple to install, the MDCStore Data Management Solution is also straightforward to maintain and manage with the MDCStoreTools utility.

Software Link:  MDCStore - Data Management Tool

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Seurat - Data sharing and visualization tool

Seurat: A powerful data sharing and visualization tool for all members of a discovery team

What Seurat can do for you...
- Compound and assay registration
- Search and query chemical, physical, and biological properties
- SAR: R-group analysis
- Elevate hits to leads, lead optimization, and PK analyses
- Share data with one-click Live Reports
- Plotting and visual data mining

Seurat streamlines data access and analysis from a broad mixture of in-house and in?licensed databases, reports, literature, and computational results by providing a wide array of tools for medicinal chemists, biologists, modelers, and IT professionals. Seurat is optimized specifically for small molecule screening, hit-to-lead, lead optimization, and preclinical analysis. Seurat facilitates cross?functional collaboration, resulting in better decision making and accelerated progress.

Seurat is a Rich Internet Application (RIA) that can work with any in-house and in-licensed data and present it in the most meaningful form to all members of a discovery team.

Software Link:  Seurat - Data sharing and visualization tool

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BioLT™ Literature Mining Tool

BioLT™ Literature Mining Tool
The BioLT™ Literature Mining Tool is a customizable tool for intuitive and structured text mining. BioLT version 2.0 combines biological and medical term dictionaries with powerful free-text querying capabilities. The tool provides comprehensive and structured answers to complex questions. Search results can be used for iterative refinement and extension of queries.

BioLT results can be made part of larger semantic networks within the BioXM Knowledge Management Environment. Text-mining information, such as relationships between genes, diseases and compounds can be graphically displayed, curated and linked. For example, Biomax provides the Oncology Knowledge Base data in the BioXM system.

Benefits:
Overcomes cumbersome and laborious search strategies
Supports keyword-driven and hypothesis-driven searches
Provides fast generation of domain-specific overviews
Extracts comprehensive and structured information using extendable biomedical dictionaries
Supports project-driven biomedical text analyses
Provides literature data for inclusion in knowledge management systems

Features:
Complete and precise data mining from free text
Powerful query language (using Boolean operators, dictionaries, wildcards and topics)
Large and extendable biomedical dictionary foundation (covers diseases, genes, compounds, taxonomy, etc.)
Automatic vocabulary generation for any domain
Acronym detection tool for greater precision
Several ranking methods (chi-square, cosine, etc.)

Flexible access:
Yearly subscription to the Biomax Web portal to extract information from the MEDLINE database using any common Web browser
Customized installation to extract information from other public or proprietary text sources

Software Link: BioLT™ Literature Mining Tool

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ChemBioViz - visualization and analysis Software

This premier visualization and analysis suite includes ChemBioFinder Ultra 12.0 (with ChemBioViz Pro 12.0), ChemBioDraw Ultra 12.0, ChemBio3D Ultra 12.0, ChemBio3D interfaces to Schrodinger's Jaguar and Gaussian, GAMESS Pro 12.0, ChemDraw/Excel and CombiChem/Excel, STATISTICA Base, MNova Std/Lite, the ChemDraw and Chem3D ActiveX Pro Plugins & Controls, and ChemScript Pro 12.0.

ChemBioViz Ultra 12.0 adds ChemBioFinder Ultra, ChemBioDraw Ultra, ChemBio3D Ultra, ChemBio3D interfaces to Schrodinger's Jaguar and Gaussian, ChemDraw/Excel and CombiChem/Excel, ChemNMR, Name=Struct, ClogP, and ChemScript Pro to ChemBioViz Pro 12.0.

ChemBioViz Ultra 12.0 provides the premier ChemBioOffice 2010 applications in a tightly integrated visualization suite, allowing users to visualize and analyze their structures and data graphically, and identify trends and correlations within subsets of data. Retrieve or search for a set of compounds, choose the data you want to see, whether it is biological test results, physical property values calculated automatically or prices in a catalog, and ChemBioViz will generate an interactive window showing a scatterplot, histogram, or other useful data graphic. Show Property predictions Live-Linked to the structure, Fragmentation tools, 3D structures Live-Linked to the 2D structure and more!

Software Link : ChemBioViz - visualization and analysis Software

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BioAssay - Life science Data Management Software

BioAssay manages data from biological experiments. It is designed for chemists and biologists working on pharmaceutical, drug or gene research and is of particular value for researchers performing in vivo experiments with complex models. Integrate chemical and biological data. Query by structure or text with ChemFinder and set up Excel templates for reporting and graphing. BioAssay is available for the Windows platform only.

Software Link: BioAssay - Life science Data Management Software

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GenoscoreDB - SNP genotyping database and management software

Are you genotyping? Looking for an intelligent Data Management Solution?

GenoscoreDB is the answer: its holistic approach integrates all steps, from the design of your experiments (you can directly import data from dbSNP) to storing, managing and analysing your results. A server version allows to work from several desks and collects all in a central repository.

Software Link:  GenoscoreDB - SNP genotyping database and management software

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Progeny Lab - Genotyping Data Management software

Whether you’re managing whole genome association, targeted genotyping, or linkage studies, Progeny Lab is the ideal lab management software for all of your genetic data. Best of all, you can combine Lab with Progeny Clinical and include all of your phenotypic data in the same database, providing the power to combine both sets of data for the most thorough analysis available.

Support is included for both SNPs and STRs, providing you with the ability to natively import genotype data from such varied platforms as ABI, Affymetrix, Illumina, Sequenom, and others.

Progeny Lab incorporates a variety of error checks and has a number of time saving features streamlining the process of gene discovery.

Software Link:  Progeny Lab - Genotyping Data Management software

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BioOffice - Life science Data Management Software

This ultimate suite for management and publication of biological data includes BioDraw Ultra 12.0, ChemBio3D Ultra 12.0, ChemBioFinder Pro 12.0, ChemBioViz Pro 12.0, STATISTICA Base, BioAssay Ultra 12.0, Inventory Pro 12.0, E-Notebook Pro 12.0, ChemDraw/Excel, the ChemDraw and Chem3D ActiveX Pro Plugins & Controls as well as a the ChemINDEX (Index, RXN, NCI & AIDS) databases.

BioOffice Ultra 2010 features now available:

E-Notebook
Offline mode -- work offline and sync later
Full text search -- search contents of collections, documents, and styled text fields

Inventory
ChemACX shopping carts -- search ChemACX and use the results to request containers from suppliers by creating shopping carts
Request management -- users can request internal chemical substances which can be approved or rejected

BioAssay
Excel analysis -- export data into Excel, analyze, and re-import into BioAssay

BioDraw
Documents can contain over 16 million colors
High color biological element and pathway templates

ChemBio3D
Stochastic conformational sampling

ChemBioFinder / ChemBioViz
Clustering analysis

Software Link: BioOffice - Life science Data Management Software

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IO Informatics - Life science Data Management Software

Today life sciences industries face unprecedented demands to reduce clinical and administrative costs, manage data from myriad sources, and improve team productivity. It is vital to the success of any life-science organization to improve efficiency and cost containment.

Harnessing the explosion of data is a constant challenge for life sciences organizations. In an ever-changing environment, locating and accessing information can consume a vast amount of resources.

"The increasing number of failures in the early stages of drug development is causing a bottleneck that threatens drug makers' efforts to rebuild their inventory of new drugs, according to a top Wyeth official. 'Success rates in Phase II studies have fallen from 40% to 25% in just five years, while the time it takes for the studies to reach their conclusions has doubled to almost three years since 2000.'"

Sentient solutions for life sciences optimize the flow of data, enabling organizations to track life-cycle information from early-stage data acquisition and R&D right through to FDA submission.

"The Sentient Suite expedites our biomarker discovery, creating the ability to raise the visibility of proteins of interest and to find and link them to related information"

Using Sentient software, users can dramatically improve efficiency through integrated data analysis. Users can search, link, correlate, and manipulate data sets, including scientific data, images, databases, spreadsheets, web content, proprietary video, and file formats.

In contrast to most current data integration methods, Sentient solutions minimize disruption of existing infrastructure, use existing infrastructures, and can be installed on standard laptop computers.

Software Link:  IO Informatics - life science Data  Management Software

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IQbase - image organization Tool

IQbase image database will help you to preserve your organization's images and data while using a streamlined workflow that fits your needs.

Manage Your Valuable Image Data
Your organization spends time and money acquiring images. With IQbase, you can easily store and access this image data. Save time, save corporate knowledge, and save money.

Share and Search for Images Online
Share and search for archived images online via the web.

Quickly Find What You are Looking For
Use sophisticated search and query tools to find exactly what you are looking for. Locate images using metadata, keywords and other related information.

Streamline Your Workflow
IQbase offers a flexible interface that lets you archive and access images using techniques that fit your workflow.

Review and Compare Archived Images
Gain a better understanding of your archived images by using the many built-in tools for reviewing and comparing images data.

Report Your Findings
Share your image data using tools that allow you to quickly export to PowerPoint and create template-based reports.

Software Link: IQbase - image organization Tool

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GraphPad Prism - Data Analysis Management software

GraphPad Prism is a powerful combination of basic biostatistics, curve fitting and scientific graphing in one comprehensive program. More than 100,000 scientists in over 100 countries rely on Prism to analyze, graph and present their scientific data.

What makes Prism the program of choice for many of the world's leading universities, medical centers, research institutes and pharmaceutical companies? Prism certainly has all the capabilities you would expect from a top notch scientific graphics program, but what makes Prism truly unique is not what it does, but how it does it. Designed for the practical scientist, Prism does not expect you to be a statistician. It guides you through each analysis - giving you as much help as you need - and tracks and organizes your work like no other program available. You can concentrate on your data, not fight with your software.

Software Link : GraphPad Prism - Data Analysis Management software

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Stat-200 - Data Analysis Management software

Stat-200 is a remarkably comprehensive general statistics package. It incorporates all the descriptive statistics, parametric and non-parametric statistical tests, graphics and data transforms you will need for processing, analyzing and presenting data. Parametric tests and procedures in Stat-200 total 60 and there are 66 non-parametric tests and procedures and 30 different descriptive statistics. ANOVA is comprehensive and includes general N factor analysis. Many unusual procedures are included e.g. survival analysis. All tests have associated information windows which give literature references and other facts to assist in getting the right one for the job. Probabilities are calculated directly so there is no need to use tables.

Stat-200 has a state-of-the-art user interface with all its statistical and plotting modules easily selected from the logical tree views. Procedures you use frequently can be placed in a Favorites list for instant access. The workbook is a powerful tool for manipulating and selecting data. It can be any size, limited only by your computer hardware. More than 65 data transforms are supplied and there is a high-level language built-in to enable any transform to be programmed by the user. Data can be keyed-in and also either copied and pasted or dragged and dropped from spreadsheets. In addition, spreadsheet files in many formats can be directly opened. Stat-200 is readily integrated with databases and it supports Recordset tables for ODBC database connections enabling data and results to be easily passed back and forth.

Software LInk : Stat-200 - Data Analysis Management software

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GraphPad InStat - Biostatistics Software

Most statistics programs are designed by statisticians, for statisticians. These programs are feature-packed and powerful, but can overwhelm scientists with thick manuals, obscure statistical jargon and high prices. GraphPad InStat is different. InStat is designed by a scientist for scientists.

Five reasons why you should choose InStat:
InStat guides you step by step
InStat conquers the learning curve by escorting you through statistical analyses. You'll master the program in just a few minutes - really.

Clear analysis choices with explanations
You don't have to know the name of the test you need. InStat helps you pick an appropriate test by asking questions about your data. If you are unsure, consult the extensive help screens, which explain the statistical reasoning in plain language.

Easy to understand results
InStat does not assume that you are a statistics whiz. It presents results in simple paragraphs, with a minimum of statistical jargon. InStat's help screens review the use of each test and explain every portion of the results.

Unique analysis checklists
With other statistics software, it is too easy to get the right answer to the wrong question. That's why InStat provides a unique analysis checklist. Double-check that your data have not violated any assumptions of the test, and that you have picked a test that matches your experimental design and really answers the question you had in mind.

A bargain
Most other statistics programs cost several hundred dollars, but we've made InStat affordable for everyone. InStat costs only $149 for single copies and $79 for upgrades. Buy InStat right now.

Software Link: GraphPad InStat -  Biostatistics Software

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FigSys v.2.4 - Data Analysis Management software

FigSys v.2.4 is a program for processing, analyzing and presenting data and creating science documents of all kinds. FigSys is a major advance in Windows graphics software. It is powerful but easily accessible to users of all levels of experience. Turning your data into basic figure types such as line graphs, bar charts, areagrams, drop-plots or scatter diagrams is completely automatic and there are endless refinements which can be added with the simple-to-use tools. Text-only charts can be created and 3D data graphing is also included.

FigSys has advanced spreadsheet and word-processing power and entire reports and posters can be created without using other software. However, the program is easily interfaced with other software and can import and export data and images from/to a variety of sources. Data processing is comprehensive with many transforms and statistics supplied.

FigSys has powerful multivariable equation-fitting which includes a unique genetic algorithm for creating accurate initial parameter estimates. Many standard equations are supplied and you can easily add your own in conventional algebra. There is also a 'freehand' curve facility which enables you to insert smooth graph lines exactly where your eye tells you they should be.

Presentation quality output can be made to all Windows-supported devices such as printers and slide-makers and also to a wide variety of image formats for transfer to word-processors, slide bureaus etc. Template facilities in FigSys let you use a similar design of figure repeatedly with different datasets. Zoom and snap-to-grid features enable precise positioning of all the components in your document. You can reprogram the toolbars to suit your own style of working. The feature-set of FigSys can optionally be controlled by your own scripts.

Software Link: FigSys v.2.4 - Data Analysis  Management software

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